Expanding the Peptide Universe: Chemically Engineering Macrocycles for Next-Gen Hit Discovery
Time: 11:30 am
day: Day One
Details:
- Introducing non-natural peptide macrocycles by chemoselective and site-selective modification of natural peptides
- Diversifying phage-displayed peptide libraries by integrating synthetic structural motifs that exceed natural peptide chemical space
- Discovering screening innovations enabling multi-cyclized, non-natural peptides to mimic antibody functionality
