Methods for the Discovery, Evaluation & Characterization of New Ligands for Targeted Protein Degradation
Time: 9:30 am
day: Conf Day 2
Details:
- Identifying new E3 ligase interactions that can be harnessed against undruggable targets
- Generating actionable insights that can be used for further hit ID cascades
- Presenting methods for proximity labeling of a target of interest for identifying complex members and transient interactions
- Developing HTS methods to identify new molecules for targeted protein degradation
- Optimizing data analysis tools for protein degrader molecular properties
- Guiding protac SAR using quantitative measurement of biochemical properties and degradation activities
