Brian Sparling

Company: Accent Therapeutics

Job title: Director & Head of Chemistry, Drug Metabolism & Pharmacokinetics

Seminars:

Boosting Confidence in Early-Stage Drug Candidates Through Orthogonal Readouts & SAR Analysis 2:45 pm

• Integrating multiple assay platforms to validate hit specificity for targeting DHX9 and KIF18A • Adopting a SAR analysis approach for fine-turning compound structure and improving bioactivity • Combining assay expertise with deep cancer biology to succeed in hit binding and minimize off-target effectsRead more