Ben Davis

Ben Davis

Company: Vernalis

Job title: Research Fellow and Director of Business Development

Seminars:

Combining Multiple Hit ID Approaches to Successfully Tackle Challenging Targets 9:45 am

2-epimerase is a promising antibacterial target proposed to synergise with clinically important antibiotics Conformational flexibility, cryptic pockets and a large polar binding site make this a challenging target  Combining multiple hit ID approaches, including FBLD, MTS and a proprietary fragment-DEL technology, has generated nM inhibitors which show strong synergistic potentiation of beta-lactam antibioticsRead more

day: Conf Day 1

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